George M. Carman, Ph. D.

Montero-Moran, G., J. M. Caviglia, D. McMahon, A. Rothenberg, V. Subramanian, Z. Xu, S. Lara-Gonzalez, J. Storch, G.M. Carman, and D.L. Brasaemle.  2009.  CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase. J. Lipid Res.  in press.

Elswaifi, S. F., F. St. Michael, A. Sreenivas, A. Cox, G.M. Carman, and T.J. Inzana.  2009. Molecular characterization of phosphorylcholine expression on the lipooligosaccharide of Histophilus somni. Microb.Pathog. 47: 223-230. Reprint

Grimsey, N., G. S. Han, L. O’ Hara, J. J. Rochford, G. M. Carman, and S. Siniossoglou. 2008.  Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2.  J. Biol. Chem. 283; 29166-29174. Reprint

Han, G.-S., L. O’ Hara, G.M. Carman, and S. Siniossoglou.  2008.  An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth.  J. Biol. Chem. 283: 20433-20442. Reprint (JBC Paper of the Week)

Han, G.-S., L. O’ Hara, S. Siniossoglou, and G.M. Carman.  2008.  Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase.  J. Biol. Chem. 283: 20443-20453.Reprint (JBC Paper of the Week)

Nadra, K., A.-S. de Preux Charles, J.-J. Médard, W.T. Hendriks, G.-S. Han, S. Grès, G.M. Carman, J.-S.  Saulnier-Blache, M.H.G. Verheijen, and R. Chrast.  2008.  Phosphatidic acid mediates demyelination in Lpin1 mutant mice.  Genes Dev. 22, 1647-1661. Reprint

Soto, A., and G.M. Carman.  2008.  Regulation of the Saccharomyces cerevisiae CKI1-encoded choline kinase by zinc depletion. J. Biol. Chem. 283: 10079-10088. Reprint

Havriluk, T., F. Lozy, S. Siniossoglou, and G.M. Carman.  2008.  Colorimetric determination of pure Mg2+-dependent phosphatidate phosphatase activity.  Anal. Biochem.  373: 392-394. Reprint

Han, G.-S., S. Siniossoglou, and G.M. Carman.  2007.  The cellular functions of the yeast lipin homolog Pah1p are dependent on its phosphatidate phosphatase activity.  J. Biol. Chem. 282: 37026-37035. Reprint

Choi, H.-S., and G.M. Carman. 2007. Respiratory deficiency mediates the regulation of CHO1-encoded phosphatidylserine synthase by mRNA stability in Saccharomyces cerevisiae. J. Biol. Chem. 282: 31217-31227. Reprint

Chang, Y.-F., S.S. Martin, E.P. Baldwin, and G.M. Carman.  2007.  Phosphorylation of human CTP synthetase 1 by protein kinase C. Identification of Ser462 and Thr455 as major sites of phosphorylation.  J. Biol. Chem. 282: 17613-17622. Reprint

Choi, M.-G., and G.M. Carman.  2007.  Phosphorylation of human CTP synthetase 1 by protein kinase A. Identification of Thr455 as a major site of phosphorylation.  J. Biol. Chem. 282: 5367-5377. Reprint

O’Hara, L., G.-S. Han, S. Peak-Chew, N. Grimsey, G.M. Carman, and S. Siniossoglou.  2006.  Control of phospholipid synthesis by phosphorylation of the yeast lipin Pah1p/Smp2p Mg2+-dependent phosphatidate phosphatase. J. Biol. Chem. 281: 34537-34548 Reprint

Han, G. S., W.-I. Wu, and G.M. Carman.  2006.  The Saccharomyces cerevisiae lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme.  J. Biol. Chem. 281: 9210-9218. Reprint (JBC Paper of the Week and News Release)

Kersting, M.C., and G.M. Carman.  2006.  Regulation of the Saccharomyces cerevisiae EKI1-encoded ethanolamine kinase by zinc depletion. J. Biol. Chem. 281: 13110-13116. Reprint

Chang, Y.-F., and G.M. Carman.  2006. Casein kinase II phosphorylation of the yeast phospholipid synthesis transcription factor Opi1p. J. Biol. Chem. 281: 4754-4761. Reprint

Reviews

Carman, G.M., and G.-S. Han.  2009.  Phosphatidic acid phosphatase, a key enzyme in the regulation of lipid synthesis.  J. Biol. Chem. 284: 2593-2597. Reprint

Carman, G.M., and G.-S. Han.  2009.  Regulation of phospholipid synthesis in yeast.  J. Lipid Res. 50: S69-S73. Reprint

Chang, Y.-F., and G.M. Carman.  2008.  CTP synthetase and its role in phospholipid synthesis in the yeast Saccharomyces cerevisiae.  Prog. Lipid Res. 47: 333-339. Reprint

Carman, G.M., and S.A. Henry.  2007.  Phosphatidic acid plays a central role in the transcriptional regulation of glycerophospholipid synthesis in Saccharomyces cerevisiae. J. Biol. Chem. 282: 37293-37297. Reprint

Carman, G.M., and G.-S. Han.  2007.  Regulation of phospholipid synthesis in Saccharomyces cerevisiae by zinc depletion.  Biochim. Biophys. Acta. 1771: 322-330. Reprint

Carman, G.M., and G.-S. Han.  2006.  Roles of phosphatidate phosphatase enzymes in lipid metabolism.  Trends Biochem. Sci. 31: 694-699. Reprint

Carman, G. M.  2005.  Regulation of phospholipid synthesis in yeast by zinc.  Biochem. Soc.Trans. 33: 1150-1153. Reprint

Carman, G.M., and M.C. Kersting.  2004.  Phospholipid synthesis in yeast: regulation by phosphorylation.  Biochem. Cell Biol. 82: 62-70. Reprint

Han, G.-S., and G.M. Carman.  2004.  Phospholipid synthesis in yeast, in Encyclopedia of Biological Chemistry (W.J. Lennarz and M.D. Lane, eds), Elsevier, Oxford. 3: 321-325.

Oshiro, J., G.-S. Han, and G.M. Carman.  2003.  Diacylglycerol pyrophosphate phosphatase in Saccharomyces cerevisiae.  Biochim. Biophys. Acta 1635: 1-9. Reprint

Kent, C., and G.M. Carman.  1999.  Interactions among pathways for phosphatidylcholine metabolism, CTP synthesis and secretion through the Golgi apparatus.  Trends Biochem. Sci. 24: 146-150. Reprint

Carman, G.M. and S.A. Henry.  1999.  Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes.  Prog. Lipid Res. 38: 361-399.

Carman, G.M., and G.M. Zeimetz. 1996. Regulation of phospholipid biosynthesis in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 271: 13292-13296. Reprint

Carman, G.M. 1997.  Phosphatidate phosphatases and diacylglycerol pyrophosphate phosphatases in Saccharomyces cerevisiae and Escherichia coli.  Biochim. Biophys. Acta  1348: 45-55. Reprint

Carman, G.M., R.A. Deems, and E.A. Dennis. 1995. Lipid signaling enzymes and surface dilution kinetics. J. Biol. Chem. 270: 18711-18714. Reprint