Michael L. Chikindas, Ph. D.

 

 

 

REFEREED PUBLICATIONS

M.L. Chikindas, R. Weeks, D. Drider, V.A. Chistyakov, and L.M.T. Dicks. 2017. Functions and emerging applications of bacteriocins. Current Opinion in Biotechnology 49:23–28.

A.Z. Pepoyan, M.H. Balayan, A.M. Manvelyan, V. Mamikonyan,  M. Isajanyan, V.V. Tsaturyan, S. Kamiya, V. Netrebov, and M. L. Chikindas. 2017. Lactobacillus acidophilus probiotic regulates growth of commensal Escherichia coli in gut microbiota of familial Mediterranean fever disease subjects. Letters in Applied Microbiology 64:254-260.

A. Algburi, S. Zehm, V. Netrebov, A.B. Bren, V. Chistyakov, and M.L. Chikindas. 2017. Subtilosin prevents biofilm formation by inhibiting bacterial quorum sensing. Probiotics and Antimicrobial Proteins 9:81-90.

A. Algburi, N. Comito, D. Kashtanov, L.M.T. Dicks, and M.L. Chikindas. 2017. Control of biofilm formation: antibiotics and beyond. Applied and Environmental Microbiology 83:e02508-16.  https://doi.org/10.1128/AEM.02508-16.

Yingyue Zhang, Ammar Algburi, Ning Wang, Vladyslav Kholodovych, Drym O. Oh, Michael Chikindas, and Kathryn E. Uhrich. 2017. Self-assembled cationic amphiphiles as antimicrobial peptides mimics: Role of hydrophobicity, linkage type, and assembly state. Nanomedicine: Nanotechnology, Biology, and Medicine 13:343-352.

Djamel Drider, Farida Bendali, Karim Naghmouchi, and Michael L. Chikindas. 2016. Bacteriocins: not only antibacterial agents. Probiotics and Antimicrobial Proteins 8:177-182.

Aabha Gupta, Michael Chikindas, Victoria Netrebov, and Santosh Kumar Tiwari. 2016. Mechanism of action of enterocin LD3 purified from Enterococcus hirae strain LD3. Probiotics and Antimicrobial Proteins 8:161-169.

A. Al-Gburi, A. Volski, C. Cugini, E.M. Walsh, V.A. Chistyakov, M.S. Mazanko, A.B. Bren, and M.L. Chikindas. 2016. Safety properties and probiotic potential of Bacillus subtilis KATMIRA1933 and Bacillus amyloliquifaciens B-1895. Advances in Microbiology 6:432-452.

O.A. Nikiforova, S. Klykov, A. Volsky, L.M.T. Dicks, and M.L. Chikindas. 2016. Effect of medium compounds on the antimicrobial activity of subtilosin produced by Bacillus subtilis KATMIRA1933. Annals of Microbiology 66:661-667.

O.K. Topuz, E.B. Özvural, Q. Zhao, Q. Huang, M. Chikindas, and M. Gölükçü. 2016. Physical and antimicrobial properties of anise oil loaded nanoemulsions on the survival of foodborne pathogens. Food Chemistry 203:117–123.

E.B. Özvural, Q. Huang, and M.L. Chikindas. 2016. The comparison of the quality and microbiological characteristics of hamburger patties enriched with green tea extract using three techniques: Direct addition, edible coating and encapsulation. LWT - Food Science and Technology 68:385-390.
E.V. Prazdnova, V.A. Chistyakov, M.N. Churilov, M.S. Mazanko, A.B. Bren, A. Volski, and M.L. Chikindas. 2015. DNA-protection and antioxidant properties of fermentates from Bacillus amyloliquefaciens B-1895 and Bacillus subtilis KATMIRA1933. Letters in Applied Microbiology 61:549-554.
A. Faig, T.D. Arthur, P.O. Fitzgerald, M. Chikindas, E. Mintzer, and K.E. Uhrich (2015) Biscationic tartaric acid-based amphiphiles as antimicrobials: influence of charge location. Langmuir 31:11875-11885.
V. Cavera, T. Arthur, D. Kashtanov, and M.L. Chikindas. 2015. Bacteriocins and their position in the next wave of conventional antibiotics. International Journal of Antimicrobial Agents 46:494-501.
A. Al-Gburi, A. Volski, and M.L. Chikindas. 2015. Natural antimicrobials subtilosin and lauramide arginine ethyl ester (LAE) synergize with conventional antibiotics clindamycin and metronidazole against biofilms of Gardnerella vaginalis but not against biofilms of healthy vaginal lactobacilli. FEMS Pathogens and Diseases 73(5):12 pages. DOI: 10.1093/femspd/ftv018
V.L. Cavera, A. Volski, and M.L. Chikindas. 2015. The natural antimicrobial subtilosin A synergizes with lauramide 1 arginine ethyl ester (LAE), epsilon-poly-L-lysine (polylysine), clindamycin phosphate and metronidazole, against the vaginal pathogen Gardnerella vaginalis. Probiotics and Antimicrobial Proteins 7:164-171.
N. Sonsa-Ard, S. Rodtong, M.L. Chikindas, and J. Yongsawatdigul. 2015. Characterization of bacteriocin produced by Enterococcus faecium CN-25 isolated from traditionally Thai fermented fish roe. Food Control 54:308-316.
S.K. Tiwari, K. Sutyak Noll, V. Cavera, and M.L. Chikindas. 2015. Improved antimicrobial activity of synthetic-hybrid bacteriocins designed from enterocin E50-52 and pediocin PA-1. Applied and Environmental Microbiology 81:1661-1667.
N. Gaaloul, O. ben Braik, K. Hani, A. Volski, M.L. Chikindas, and T. Ghrairi. 2015. Isolation and characterization of large spectrum and multiple bacteriocinsproducing Enterococcus faecium strain from raw bovine milk. Journal of Applied Microbiology 118:343-355.
V. Chistyakov, V. Melnikov, M.L. Chikindas, M. Khutsishvili, A. Chagelishvili, A. Bren, N. Kostina, V. Cavera, and V. Elisashvili. 2015. Poultry-beneficial solid-state Bacillus amyloliquefaciens B-1895 fermented soy bean formulation. Bioscience of Microbiota, Food and Health 34:25-28.
N. Gaaloul, O. Ben Braiek, J.M. Berjeaud, T. Arthur, V. Cavera, M.L. Chikindas, K. Hani, and T. Ghrairi. 2014. Evaluation of antimicrobial activity and safety aspect of Enterococcus italicus GGN10 strain isolated from Tunisian cow raw milk. Journal of Food Safety 34:300-311.
V. Abramov, V. Khlebnikov, I. Kosarev, G. Bairamova, R. Vasilenko, N. Suzina, A. Machulin, V. Sakulin, N. Kulikova, N. Vasilenko, A. Karlyshev, V. Uversky, M.L. Chikindas, and V. Melnikov. 2014. Probiotic  properties of Lactobacillus crispatus 2029: homeostatic interaction with cervicovaginal epithelial cells and antagonistic activity to genitourinary pathogens. Probiotics and Antimicrobial Proteins 6:165–176.
V.M. Quintana, N.I. Torres, M.B. Wachsman, P.J. Sinko, V. Castilla, and M.L. Chikindas. 2014. Antiherpes simplex virus type 2 activity of the antimicrobial peptide subtilosin.Journal of Applied Microbiology 117: 1253-1259.
S.S. Rajan, Y. Turovskiy, Y. Singh, M.L. Chikindas, and P.J. Sinko. 2014. Poly(ethylene glycol) (PEG)-lactic acid nanocarrier-based degradable hydrogels for restoring the vaginal microenvironment. Journal of Controlled Release 194: 301-309.
A.V. Karlyshev, V.G. Melnikov, and M.L. Chikindas. 2014. Draft genome sequence of Bacillus subtilis strain KATMIRA1933. Genome Announcements 2(3):e00619-14. doi:10.1128/genomeA.00619-14.
M.L. Chikindas. 2014. Probiotics and atimicrobial peptides: the creatures’ and substances’ future in the twenty-first century: An opinion letter. Probiotics and Antimicrobial Proteins 6: 69-72.
L. Wassef, R. Wirawan, M. Chikindas, P. Breslin, D. Hoffman, and L. Quadro. 2014. -carotene-producing bacteria residing in the intestine provide vitamin A to mouse tissues in vivo. The Journal of Nutrition 144: 608-613.
S.S. Rajan, V. Cavera, X. Zhang, Y. Singh, M.L. Chikindas, and P.J. Sinko. 2014. Poly(ethylene glycol) (PEG)- based hydrogels for the controlled release of the antimicrobial subtilosin, for prophylaxis of bacterial vaginosis (BV) and HIV. Antimicrobial Agents and Chemotherapy 58: 2747-2753.
T.D. Arthur, V.L. Cavera, and M.L. Chikindas. 2014. On bacteriocin delivery systems and potential applications. Future Microbiology 9:235-248.
S. Xu, V. Cavera, M. Rogers, Q. Huang, K. Zubovskiy, and M.L. Chikindas. 2013. Benzoyl peroxide formulated polycarbophil/carbopol® 934P hydrogel with selective antimicrobial activity, potentially beneficial for treatment and prevention of bacterial vaginosis.Infectious Diseases in Obstetrics and Gynecology. Volume 2013, Article ID 909354, 10 pages. http://dx.doi.org/10.1155/2013/909354
N.I. Torres, K. Sutyak Noll, S. Xu, J. Li, Q. Huang, P.J. Sinko, M.B. Wachsman and M.L. Chikindas. 2013. Safety, formulation, and in vitro antiviral activity of the antimicrobial peptide subtilosin against herpes simplex virus type 1. Probiotics and Antimicrobial Proteins 5:26-36.
D. Gawkowski and M. L. Chikindas. 2013. Non-dairy probiotic beverages: next step into human health. Beneficial Microbes. 4:127-142.
Y. Turovskiy, T. Cheryian, R.E. Wirawan, P. Takhistov, P.J. Sinko and M.L. Chikindas. 2012. Susceptibility of Gardnerella vaginalis biofilms to natural antimicrobials subtilosin, ε-poly-L-lysine and lauramide arginine ethyl ester. Infectious Diseases in Obstetrics and Gynecology, Volume 2012, Article ID 284762, 9 pages, doi:10.1155/2012/284762.
S. Riazi, S.E. Dover, and M.L. Chikindas. 2012. Mode of action and safety of lactosporin, a novel antimicrobial protein produced by Bacillus coagulans ATCC 7050. Journal of Applied Microbiology 113: 714-722.
K. Sutyak Noll, M.N. Prichard, A. Khaykin, P.J. Sinko, and M.L. Chikindas. 2012. The natural antimicrobial peptide subtilosin acts synergistically with glycerol monolaurate, lauric arginate, and ε-poly-L-lysine against bacterial vaginosis-associated pathogens but not human lactobacilli. Antimicrobial Agents and Chemotherapy 56: 1756-1761.
S. van Kuijk, K.S. Noll and M.L. Chikindas. 2011. The species-specific mode of action of the antimicrobial peptide subtilosin against Listeria monocytogenes Scott A. Letters in Applied Microbiology 54: 52–58
A. Pepperney and M.L. Chikindas.
2011. Antibacterial peptides: opportunities for prevention and treatment of dental caries. Probiotics and Antimicrobial Proteins 3: 68-96.
A. Balasubramanian, D.S. Lee, M.L. Chikindas and K.L. Yam. Effect of nisin’s controlled release on microbial growth as modeled for Micrococcus luteus. Probiotics and Antimicrobial Proteins 3: 113-118.
Y. Turovskiy and M.L. Chikindas. 2011. Zinc lactate and sapindin act synergistically with lactocin 160 against Gardnerella vaginalis. Probiotics and Antimicrobial Proteins 3: 144-149.
Y. Turovskiy, K. Sutyak Noll and M.L. Chikindas. 2011. The etiology of bacterial vaginosis. Journal of Applied Microbiology 110: 1105-1128.
K. Sutyak Noll, P.J. Sinko and M.L. Chikindas. 2011. Elucidation of the molecular mechanisms of action of the natural antimicrobial peptide subtilosin against the bacterial vaginosis-associated pathogen Gardnerella vaginalis. Probiotics and Antimicrobial Proteins 3: 41-47.
M. Chikindas. 2010. New initiative for humanities granting opportunities: how reality differs from “official information”. Journal of Irreproducible Results 51(2): 30-33.
T. Amrouche, K. Sutyak Noll, Y. Wang, Q. Huang, and M.L. Chikindas. 2010. Antibacterial activity of subtilosin alone and combined with curcumin, poly-lysine and zinc lactate against Listeria monocytogenes strains. Probiotics and Antimicrobial Proteins 2: 250-257.
M. Chikindas, E. Emond, A. J. Haandrikman, J. Kok, K. Leenhouts, S. Pandian, K. Venema and G. Venema.  2010. Heterologous processing and export of the bacteriocins pediocin PA-1 and lactococcin A in Lactococcus lactis: a study with leader exchange. Probiotics and Antimicrobial Proteins 2: 66-76.
C. Murdock, M.L. Chikindas, and Karl R. Matthews. 2010. The pepsin hydrolysate of bovine lactoferrin causes a collapse of the membrane potential in Escherichia coli O157:H7. Probiotics and Antimicrobial Proteins 2: 112-119.
N. Mazundar, M. Chikindas and K. Uhrich. 2010. Slow release polymer-iodine tablets for disinfection of   untreated surface water. Journal of Applied Polymer Science 117: 329-334.
A. Balasubramanian, L.E. Rosenberg, K. Yam and M.L. Chikindas.2009. Antimicrobial packaging: potential VS reality. Journal of Applied Packaging Research 3: 193-221.
P. Takhistov, B. George and M.L. Chikindas. 2009. Listeria monocytogenes’ step-like response to sub-lethal concentrations of nisin. Probiotics and Antimicrobial Proteins 1: 159-162.
M. Badaoui Najjar, D. Kashtanov and M.L. Chikindas. 2009. Natural antimicrobials ε-poly-L-lysine and nisin A for control of oral microflora. Probiotics and Antimicrobial Proteins 1: 143-147.
M.Z. Badaoui Najjar, M.L. Chikindas and T.J. Montville. 2009. The acid tolerance response alters membrane fluidity and induces resistance to nisin in Listeria monocytogenes. Probiotics and Antimicrobial Proteins 1: 130-135.
M. Tabak, K. Scher, M. Chikindas and S. Yaron. 2009. The synergistic activity of triclosan and ciprofloxacin on biofilms of Salmonella Typhimurium. FEMS Microbiology Letters 301: 69-76.
S. Riazi, R.E. Wirawan, V. Badmaev and M.L. Chikindas.  2009. Characterization of lactosporin, a novel antimicrobial protein produced by Bacillus coagulans ATCC 7050. Journal of Applied Microbiology 106: 1370-1377.
Y. Turovskiy, R.D. Ludescher, A.A. Aroutcheva, S. Faro and M. L. Chikindas. 2009. Lactocin 160, a putative bacteriocin produced by vaginal Lactobacillus rhamnosus, targets cytoplasmic membranes of the vaginal pathogen, Gardnerella vaginalis. Probiotics and Antimicrobial Proteins 1: 67-74.
S.E. Dover, A.A. Aroutcheva, S. Faro and M.L. Chikindas. 2008. Natural antimicrobials and their role in vaginal health: a short review. International Journal of Probiotics and Prebiotics 3: 219-230.
K.E. Sutyak, R.A. Anderson, S.E. Dover, K.A. Feathergill, A.A. Aroutcheva, S. Faro and M.L. Chikindas. 2008. Spermicidal activity of the safe natural antimicrobial peptide subtilosin. Infectious Diseases in Obstetrics and Gynecology Vol. 2008, Article ID 540758, 6 pages.  
L.E. Rosenberg, A.L. Carbone, U. Römling, K.E. Uhrich and M.L. Chikindas. 2008. Salicylic acid-based poly(anhydride-esters) for control of biofilm formation in Salmonella enterica serovar Typhimurium. Letters in Applied Microbiology 46: 593-599.
K. Sutyak, R.E. Wirawan, A.A. Aroutcheva and M.L. Chikindas. 2008. Isolation of the Bacillus subtilis antimicrobial peptide subtilosin from the dairy product-derived Bacillus amyloliquefaciens. Journal of Applied Microbiology 104: 1067-1074.
S.E.  Dover, A.A. Aroutcheva, S. Faro and M.L. Chikindas. 2007. Safety study of an antimicrobial peptide lactocin 160, produced by the vaginal Lactobacillus rhamnosus. Infectious Diseases in Obstetrics and Gynecology. Vol. 2007, Article ID 78248, 6 pages.
Y. Turovskiy, L. Rosenberg and M. L. Chikindas. Quorum sensing is not involved in Listeria monocytogenes’ adaptive responses to food preservatives lactic acid and nisin. 2007. Journal of Food Safety 27: 386-399.
M. Badaoui Najjar, M.L. Chikindas and T.J. Montville. Changes in Listeria monocytogenes membrane fluidity in response to temperature stress. 2007. Applied and Environmental Microbiology 73: 6429-6435.
S. Riazi, S. Dover, Y. Turovskiy and M.L. Chikindas. 2007. Commercial ampholytes used for isoelectric focusing may interfere with bioactivity based purification of antimicrobial peptides. Journal of Microbiological Methods 71:87-89.
Y. Turovskiy, D. Kashtanov, B. Paskhover and M. L. Chikindas. 2007. Quorum sensing: fact, fiction and everything in between. Advances in Applied Microbiology 62: 191-234.
M. Badaoui Najjar, D. Kashtanov and M. L. Chikindas. 2007. e-poly-L-lysine and nisin A act synergistically against Gram-positive foodborne pathogens Bacillus cereus and Listeria monocytogenes. Letters in Applied Microbiology 45: 13-18.
C.A. Murdock, J. Cleveland McEntire, K.M. Matthews and M.L. Chikindas. 2007. The synergistic effect of nisin and lactoferrin on the inhibition of Listeria monocytogenes and Escherichia coli O157:H7. Letters in Applied Microbiology 44: 255-261.
M. Tabak, K. Scher, E. Hartog, U. Romling, K.R Matthews, M.L. Chikindas and S. Yaron.  2007. The effect of triclosan on Salmonella Typhimurium at different growth stages. FEMS Microbiology Letters 267: 200-206.
M. Gandhi and M. L. Chikindas. Listeria: A foodborne pathogen that knows how to survive.2007. International Journal of Food Microbiology 113: 1-15.
Y. Turovskiy and M. L. Chikindas. Autoinducer-2 bioassay: qualitative, not quantitative method influenced by glucose. 2006. Journal of Microbiological Methods 66: 497-503.
M. Bonnet, M.M. Rafi, M. L. Chikindas and T. J. Montville. Bioenergetic mechanism for nisin resistance, induced by the acid tolerance response of Listeria monocytogenes. 2006. Applied and Environmental Microbiology 72: 2556-2563.
J. Li, A.A. Aroutcheva, S. Faro and M.L. Chikindas. Mode of action of lactocin 160, a bacteriocin from vaginal Lactobacillus rhamnosus 160. 2005. Infectious Diseases in Obstetrics and Gynecology 13: 135-140.
R. Bauer, M.L. Chikindas and L.M.T. Dicks. Purification, partial amino acid sequence and mode of action of pediocin PD-1, a bacteriocin produced by Pediococcus damnosus NCFB 1832. 2005. International Journal of Food Microbiology 101: 17-27.
Y. Chi-Zhang, K. L. Yam and M.L. Chikindas. Effective control of Listeria monocytogenes by combination of nisin formulated and slow released into a broth system. 2004. International Journal of Food Microbiology 90: 15-22.
J. Cleveland McEntire, T. J. Montville and M.L. Chikindas. Synergy between nisin and select lactates against Listeria monocytogenes is due to the metal cations. 2003. Journal of Food Protection 66: 1631-1636.
J. Li, G. L. Kolling, K. R. Matthews and M.L. Chikindas. Cold and carbon dioxide used as multi-hurdle preservation do not induce appearance of viable but non-culturable Listeria monocytogenes. 2003. Journal of Applied Microbiology 94: 48-53.
J. Cleveland, M. Chikindas and T.J. Montville. Multi-method assessment of commercial nisin preparations.2002. Journal of Industrial Microbiology and Biotechnology 29: 228-232.
J. Li, M.L. Chikindas, R.D. Ludescher and T.J. Montville. Environmentally induced modifications alter sensitivity of Listeria monocytogenes to nisin. 2002. Applied and Environmental Microbiology 68: 5904-5910.
C.A. Van Reen, M.L. Chikindas, W.H. Van Zyl and L.M.T. Dicks. Characterization of bacteriocin 423, a class IIa antimicrobial protein from Lactobacillus pentosus and its heterologous expression in Saccharomyces cerevisiae. 2002. International Journal of Food Microbiology 81: 29-40.
C.M. Rosa, B.D.G.M. Franco, T.J. Montville and M. L. Chikindas. Purification and mechanistic action of a bacteriocin produced by a Brazilian sausage isolate. Lactobacillus sake. 2002. Journal of Food Safety 22: 39-54.
A. Fox, M. Anderson, J. Dunn, B. Guenther, L. Parks, R. Pinnick, C. Reed, J. Rowe, R. Luftig, G.W.  Long, R. Lontz, G.L. Marchin, A.T. McManus, P. Setlow, J. Siedow, A.J. Sievers, M.L. Tchikindas and S. Tove. Report of the "Bioterrorism Workshop" - Duke University Thomas Center on April 2-4, 2002, organized by US Army Research Office. 2002. Journal of Microbiological Methods 51: 247-254.
J. Cleveland, T. J. Montville, I.F. Nes and M.L. Chikindas. Bacteriocins: safe natural antimicrobials for food preservation. 2001. International Journal of Food Microbiology 71: 1-20.
C. Herranz, Y. Chen, H.-J. Chung, L. M. Cintas, P.E. Hernández, T.J. Montville and M. L. Chikindas. 2001. Enterocin P selectively dissipates the membrane potential of Enterococcus faecium T136. Applied and Environmental Microbiology 67: 1689-1692.
D. Chung, M.L. Chikindas and K.L. Yam. 2001. Inhibition of Saccharomyces cerevisiae by slow release of propyl parabene from a polymer coating. Journal of Food Protection 64: 1420-1424.
H.-J. Chung, M.L. Chikindas and T.J. Montville. Nisin depletes ATP and proton motive force in mycobacteria. 2000. Letters in Applied Microbiology 31: 416-420.
K. D. Modi, M. L.Chikindas and T. J. Montville. 2000. Sensitivity of nisin-resistant Listeria monocytogenes Scott A to heat and the synergistic action of heat and nisin. Letters in Applied Microbiology 30: 249-253.
L. Nilsson, Y. Chen, M. L. Chikindas, H. H. Huss, L. Gram and T. J. Montville. 2000. Carbon dioxide and nisin act synergistically on the cytoplasmic membrane of Listeria monocytogenes. Applied and Environmental Microbiology 66: 769-774.
T.J. Montville, H.-J. Chung, M.L. Chikindas and Y. Chen. Nisin A depletes intracellular ATP and acts in bactericidal manner against Mycobacterium smegmatis. 1999. Letters in Applied Microbiology 28: 189-194.
C.A. van Reen, L.M.T. Dicks and M.L. Chikindas. 1998. Isolation, purification and partial characterization of plantaricin 423, a bacteriocin produced by Lactobacillus plantarum. Journal of Applied Microbiology 84: 1131-1137.
G. Green, L.M.T. Dicks, G. Bruggeman, E.J. Vandamme and M.L. Chikindas. 1997. Pediocin PD-1, a bactericidal antimicrobial peptide from Pediococcus damnosus NCFB 1832. Journal of Applied Microbiology 83: 127-132.
M.L. Chikindas, J. Novák, P.W. Caufield, K. Schilling and J.R. Tagg. 1997. Microbially-produced peptides having potential application to the prevention of caries. Review article. International Journal of Antimicrobial Agents 9: 95-105.
K. Venema, M.L. Chikindas, J.F.M.L. Seegers, A.J. Haandrikman, K.J. Leenhouts, G. Venema and J. Kok.1997. Rapid and efficient purification method for small, hydrophobic, cationic bacteriocins. Purification of lactococcin B from Lactococcus lactis subsp. cremoris and pediocin PA-1 from Pediococcus acidilactici PAC1.0. Applied and Environmental Microbiology 63: 305-309.
M.L. Chikindas. Bacteriocins: prospects for the prevention of caries and periodontal disease: a review. 1996. Pan-Armenian Science Review - The Official Newsletter of The Pan-Armenian Academic and Scientific Society 3: 16-25.
M. L. Chikindas, J. Novák, A.J.M. Driessen, W.N. Konings, P.W. Caufield  and K.M. Schilling. 1995. Mutacin II, a bactericidal type B lantibiotic from Streptococcus mutans. Antimicrobial Agents and Chemotherapy 39: 2656-2660.
M.L. Chikindas, K. Venema, A.M. Ledeboer, G. Venema  and J. Kok. 1995. Expression of lactococcin A and pediocin PA-1 in heterologous hosts. Letters in Applied Microbiology 21: 183 - 189.
K. Venema, J. Kok, J.D. Marugg, M.Y. Toonen, A.M. Ledeboer, G. Venema  and M.L. Chikindas. 1995. Functional analysis of the pediocin operon of Pediococcus acidilactici PAC1.0: PedB is the immunity protein and PedD is the precursor processing enzyme. Molecular Microbiology 17: 515 - 522.
V.N. Mironov, A.S. Kraev, M.L. Chikindas, B.K. Chernov, A.I. Stepanov and K.G. Skryabin. 1994. Functional organization of the riboflavin biosynthesis operon from Bacillus subtilis SHgw. Molecular and General Genetics 242: 201 - 208.
M.L. Chikindas, M.J. Garcia, A.J.M. Driessen, A.M. Ledeboer, J. Nissen-Meyer, I.F. Nes, T. Abee, W.N. Konings and G. Venema.1993. Pediocin PA-1, a bacteriocin from Pediococcus acidilactici PAC1.0, forms hydrophilic pores in the cytoplasmic membrane of target cells. Applied and Environmental Microbiology 59: 3577 - 3584.
L.I. Patrushev, A.G. Valiaev, P.A. Golovchenko, S.V. Vinogradov, M.L. Chikindas and V.I. Kiselev. 1993. Cloning of the gene for thermostable Thermus aquaticus YT1 DNA polymerase and its expression in Escherichia coli.  Molekuliarnaia Biologiia 27: 1100-1112. (Russian, English summary).
A.V. Kabanov, I.V. Astafyeva, M.L. Chikindas, G.F. Rosenblat, V.I. Kiselev, E.S. Severin and V.A. Kabanov.1991. DNA interpolyelectrolyte complexes as a tool for efficient cell transformation. Biopolymers 31: 1437 - 1443.
V.N. Mironov, M.L. Chikindas, A.S. Kraev, A.I. Stepanov and K.G. Skryabin. 1990. Operon organization of riboflavin biosynthesis genes from Bacillus subtilis. Doklady Akademii Nauk SSSR 312(1):  237 - 240 (Russian, English summary).
M.L. Chikindas, V.V. Grabovetsky, N.S. Melik-Nubarov, E.Yu. Klinsky, O.V. Vasilenko, P.G. Sveshnikov, V.Yu. Alakhov and V.I. Kiselev. 1990. Cloning and expression of the enterotoxin A gene of Staphylococcus aureus in Escherichia coli cells. Jurnal Mikrobiologii, Epidemiologii i Immunobiologii (Journal of Microbiology, Epidemiology and Immunobiology) No 2, pp. 18 - 20 (Russian).
M.L. Chikindas, S.V. Isaeva, L.G. Chistyakova, E.Yu. Klinsky, V.V. Grabovetsky, O.V. Vasilenko, P.G. Sveshnikov, V.Yu. Alakhov and V.I. Kiselev. 1990. Expression of Staphylococcus aureus gene for enterotoxin A in heterologous systems. Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya No 3. pp. 21 - 24 (Russian, English summary).
A.V. Kabanov, V.I. Kiselev, M.L. Chikindas, I.V. Astafyeva, A.I. Glukhov, S.A. Gordeev, E.S. Severin and V.A. Kabanov. 1989. Increasing DNA transformation activity by means of its incorporation into the interpolyelectrolytic complex with carbochain polycation. Doklady Akademii Nauk SSSR 306(1): 226 - 230 (Russian, English summary).
E.V. Lukyanov, M.L. Chikindas and A.I. Stepanov. 1989. Expression of the Bacillus pumilus chloramphenicol acetyltransferase gene in Bacillus subtilis from the promotor of phage l. Genetika. Vol. XXV, No 3, pp. 555 - 556 (Russian, English summary).
M.L. Chikindas, G.I. Morozov,  V.N. Mironov, E.V. Lukyanov, V.V. Emelyanov and A.I. Stepanov. 1988. Regulatory regions of the riboflavin biosynthesis operon of Bacillus subtilis. Doklady Akademii Nauk SSSR (Proceedings of the Academy of Sciences of the USSR) 298(4): 997 - 1000 (Russian, English summary).
M.L. Chikindas, V.N. Mironov and A.I. Stepanov. 1987. Localization of spo- genes in the region of 210° of Bacillus subtilis chromosome. Genetika (Genetics) Vol. XXIII, No 10, pp. 1900 - 1902  (Russian, English summary).
M.L. Chikindas, V.N. Mironov, E.V. Lukyanov, Yu.R. Boretsky, L.S. Arutyunova, P.M. Rabinovich and A.I. Stepanov. 1987. Determining the riboflavin operon bounds in Bacillus subtilis. Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya No 4, pp. 22 - 26 (Russian, English summary).
M.L. Chikindas, P.M. Rabinovich and A.I. Stepanov. 1987. Study of Bacillus subtilis 210° chromosomal region by the recombinant plasmids technique. Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya (Molecular Genetics, Microbiology and Virology) No 2, pp. 20 - 24 (Russian, English summary).

PATENTS PUBLISHED

P. Sinko, M.L. Chikindas, S. Stein, Y. Singh, S.S. Rajan, D. Gao, and K. Sutyak Noll. Multifunctional biodegradable PEG nano-carrier based hydrogels for preventing HIV transmission. US 2014/0010862 A1. Publication Date: January 9, 2014.
P. Sinko, M.L. Chikindas, S. Stein, Y. Singh, S.S. Rajan, D. Gao, and K. Sutyak Noll. Multifunctional biodegradable PEG nano-carrier based hydrogels for preventing HIV transmission. WO 2012/068179 A1. International Publication Date: 24 May 2012.
M.L. Chikindas, A. Joiner, and P.W. Small. Anti-microbial composition. US Patent 5,672,351. Filed: December 11, 1995; Issued: September 30, 1997.
S.A.Tyurin, A.P. Dobritsa, M.L. Chikindas, and A.L. Osterman. Bacterial strain of Bacillus thuringiensis T-I as a producer of d-endotoxin. Invention Certificate No 277200/13, positive resolution: June 29, 1988, (Russian).

BOOK CHAPTERS

L.M.T. Dicks, T.D.J. Heunis, D.A. van Staden, A. Brand, K. Sutyak Noll, and M.L. Chikindas. 2011. Medical and Personal Care Applications of Bacteriocins Produced by Lactic Acid Bacteria. In: Prokaryotic Antimicrobial Peptides. Djamel Drider and Sylvie Rebuffat (Editors). Springer ISBN 978-1-4419-7691-8. DOI 10.1007/978-1-4419-7692.
A.R. Guinta, A.L. Carbone, L.E. Rosenberg, K.E. Uhrich, M. Tabak and M.L. Chikindas.2009. Slow release of salicylic acid from degrading poly(anhydride ester) polymer disrupts bimodal pH and prevents biofilm formation in Salmonella typhimurium MAE52 In: Biofilms: Formation, Development and Properties. Chapter 27. (Editor: WIlliam C. Bailey).  Nova Science Publishers, Inc. ISBN: 978-1-61728-293-5.
M.L. Chikindas and T.J. Montville. 2001. Bacteriocins: perspectives for application as food preservatives. In: Control of Foodborne Microorganisms, Marcel Dekker, Inc. (eds., Juneja and Sofos).
T.J. Montville, K. Winkowski and M.L. Chikindas. 2001 Biologically based preservation systems. In: Food Microbiology: Fundamentals and Frontiers, 2nd ed., ASM Press (eds., Doyle et al.).Modified chapter appeared in the 3rd edition of the book.

THESIS (Ph.D.)

M.L. Chikindas. Structural organization of the riboflavin biosynthesis operon of Bacillus subtilis. Moscow, 1987 (Russian).

MANUSCRIPTS ACCEPTED FOR PUBLICATION

L. Wassef, R. Wirawan, M. Chikindas, P. Breslin, D. Hoffman, and L. Quadro. 2014 -carotene-producing bacteria residing in the intestine provide vitamin A to mouse tissues in vivo. Accepted for publication in: The Journal of Nutrition.

ABSTRACTS

K. Sutyak Noll, P.J. Sinko, M.L. Chikindas. 2010. HIV prevention through the control of bacterial vaginosis: the natural antimicrobial peptide subtilosin’s activity against Gardnerella vaginalis. 22nd Annual New Jersey Women and AIDS Network Conference: Confronting the Crisis. New Brunswick, New Jersey.
K. Sutyak, R. Wirawan, A. Aroutcheva, R. Anderson, S. Dover, K. Feathergill and M. Chikindas. 2009. Subtilosin; a safe antimicrobial peptide for the control of bacterial vaginosis-associated pathogens. Poster 06-MAP. Book of Abstracts. 2nd International Symposium on Antimicrobial Peptides, page 200. Saint-Malo, France, 2009.
K. E. Sutyak, R.A.A. Anderson, S.E.D. Dover,  A. A. Aroutcheva and M. L. Chikindas. 2008. Spermicidal activity and mode of action of the safe, natural antimicrobial peptide subtilosin. 9th Symposium on Lactic Acid Bacteria. Egmond aan Zee, The Netherlands, 08.31-09.04.2008.
K. E. Sutyak, R. E. Wirawan, A. A. Aroutcheva and M. L. Chikindas. 2007. Isolation of the Bacillus subtilis antimicrobial peptide subtilosin from the dairy product-derived Bacillus amyloliquefaciens. II International Conference on Environmental, Industrial and Applied Microbiology. Seville, Spain.
A.L. Carbone, L.E. Rosenberg, M.L. Chikindas and K.E. Uhrich.  2007. Design and synthesis of biodegradable polyanhydrides based on plant and food-derived natural antimicrobials for biofilm prevention. Polymer Preprints, American Chemical Society, Division of PolymerChemistry, 48(2),  730-731.
Scher K., M. Tabak, E. Hartog, K.R. Matthews, M. Chikindas and S. Yaron. The effect of triclosan and chlorine on Salmonella Typhimurium biofilm. ASM 3rd conference on Salmonella: from pathogenesis to therapeutics, Victoria, Canada. September 2006.
Tabak, M., K. Scher K., E. Hartog, U. Romling, K.R. Matthews, M. Chikindas and S. Yaron. The effect of triclosan on Salmonella Typhimurium at different growth stages and in a biofilm. International symposium “Salmonella and salmonellosis”, Saint-Malo, France, May 2006, p. 243.
Scher K., E. Hartog, M. Tabak, U. Romling, K.R. Matthews, M. Chikindas and S. Yaron. The effect of triclosan on Salmonella Typhimurium cells at different growth stages and in a biofilm. Israel Society for Microbiology, Annual Meeting, Beer Sheva, February 2006, p. 109.
M. L. Chikindas,  A. Aroutcheva and S. Faro. “Natural antimicrobial peptides for control of vaginal pathogens”. Book of Abstracts. First international Symposium on Antimicrobial Peptides. Food, Veterinary, and Medical Applications. D. Drider and H. Prevost, eds. Nantes, France, June 21-23, 2006, p. 30.
M. L. Chikindas, D. Kashtanov and Y. Turovskiy. Autoinducer-2 bioassay is a qualitative, not quantitative method influenced by glucose. Book of Abstracts. Theobald Smith Society 2006 Meeting in Miniature. April 2006.
A. Aroutcheva, M. L. Chikindas and S. Faro. “Lactocin 160 for intravaginal microbicide”. International Conference on Women and Infectious Diseases. March 16, 2006. ICWID, 2006, 88.
A. Aroutcheva, S. Faro and M. L. Chikindas. “Natural antimicrobial peptides in food preservation and personal care”.  Book of  Abstracts. Symposium “Bioactive Peptides”, 97th AOCS Annual Meeting & Expo, April 30-May 3, 2006, St. Louis, Missouri.
A. Aroutcheva, J. A. Simoes, M. Chikindas and S. Faro. 2002.Effect of lactocin 160 on BV-associated organisms. 7th Annual Conference on Women's Health: International Infectious Diseases Society for Obstetrics and Gynecology – USA. Journal of Infectious Diseases in Obstetrics and Gynecology. 10 (2):117.
C.A. van Reenen, L.M.T. Dicks, M.L. Chikindas and W.H. van Zyl. Genetic characterizations of plantaricin 423, a bacteriocin from Lactobacillus plantarum. Signs of horizontal gene transfer. Seventh Symposium on Lactic Acid Bacteria. Egmond aan Zee, The Netherlands, September 1-5, 2002.
R. Bauer, M.L. Chikindas and L.M.T Dicks. Mode of action of pediocin PD-1, an antimicrobial peptide produced by Pediococcus damnosus NCFB 1832 against Oenococcus oeni. Seventh Symposium on Lactic Acid Bacteria. Egmond aan Zee, The Netherlands, September 1-5, 2002.
J. Li, T. Montville, R. Ludescher and M.L. Chikindas. Modification in membrane proteins regulate the sensitivity of Listeria monocytogenes to nisin. Seventh Symposium on Lactic Acid Bacteria. Egmond aan Zee, The Netherlands, September 1-5, 2002.
Y. Zhang, M.L. Tchikindas K. Yam. 2001. A sensitive assay method for measurement of nisin release from nisin-embedded packaging materials. Page 19, Abstract 15A-17. 2001 IFT Annual Meeting (New Orleans, LA, USA, June 23-27, 2001). IFT, 221 N. LaSalle St., Suite 300, Chicago, Illinois 60601.
J.E. Cleveland and M.L. Tchikindas. 2001. Inhibition of Escherichia coli O157:H7 and Listeria monocytogenes Scott A by synergistic action of lactoferrin and nisin. Page 142, Abstract 59E-9. 2001 IFT Annual Meeting (New Orleans, LA, USA, June 23-27, 2001). IFT, 221 N. LaSalle St., Suite 300, Chicago, Illinois 60601.
J. Li, M.L. Tchikindas and T.J. Montville. 2001. Temperature and surfactant influence the sensitivity of Listeria monocytogenes to nisin through modification of membrane fluidity. Page 142, Abstract 59E-9. 2001 IFT Annual Meeting (New Orleans, LA, USA, June 23-27, 2001). IFT, 221 N. LaSalle St., Suite 300, Chicago, Illinois 60601.
J. Cleveland, T. Montville and M. Chikindas. 2001. Combination of lactic acid and its salt derivatives with nisin to inhibit pathogen growth. NIZO Dairy Conference on Food Microbes 2001 (June 13-15, 2001, Ede, The Netherlands). Abstract P79. Elsevier Science, Osford, OX5 1GB, UK.
C.A. van Reenen, M.L. Chikindas, W.H. van Zyl and L.M.T. Dicks. 2001. Genetic characterization of bacteriocin 423 and expression in Saccharomyces cerevisiae. NIZO Dairy Conference on Food Microbes 2001 (June 13-15, 2001, Ede, The Netherlands). Abstract P79. Elsevier Science, Osford, OX5 1GB, UK.
M.L. Chikindas, J. Cleveland and T.J. Montville. 2000. Bacteriocins from Lactobacillus as future food preservatives. Journal of Animal Science, vol. 78/Journal of Dairy Science, vol. 83, Supplement 1, p. 10.
M.L. Chikindas, J. Cleveland, J. Li and T.J. Montville. 2000. Unrelatedness of Nisin Resistance and Antibiotic Resistance in Listeria monocytogenes. Annual Meeting of the International Association for Food Protection. Journal Of Food Protection, vol. 63, Sup. A, p. 54.
C.A. van Reen, L.M.T. Dicks and M.L. Chikindas. 2000. Comparison of bacteriocin 423 and pediocin PA-1.  BIOY2K Conference, Grahamstown.
G. Bruggeman, M. Bossu, V. Degrieck, M.L. Chikindas, E.J. Vandamme and L.M.T. Dicks. 1997. Fermentation optimization and the role of cyclodextrins in the bacteriocin production by Lactobacillus plantarum and Enterococcus sp.BFE 1071.  11th Forum for Applied Biotechnology, Ghent, Belgium.
C.A. van Reen, L.M.T. Dicks and M.L. Chikindas. Comparison of plantaricin 423 and pediocin PA-1. Sixth Symposium on Lactic Acid Bacteria. Book of Abstracts. Veldhoven, the Netherlnads, September 19/23, 1999. Abstract C74.
K.D. Modi, M.L. Chikindas and T.J. Montville. 1999. Sensitivity of nisin resistant and wild type Lysteria monocytogenes Scott A to heat and preservatives.1999. Sixth Symposium on Lactic Acid Bacteria. Book of Abstracts. Veldhoven, the Netherlnads, September 19/23, 1999. Abstract C58.
L. Nilsson, Y. Chen, M.L. Chikindas, H.H. Huss, L. Gram and T.J. Montville. 1999. The combined action of nisin and CO2 atmosphere on the cytoplasmic membrane of Listeria monocytogenes Scott A. Sixth Symposium on Lactic Acid Bacteria. Book of Abstracts. Veldhoven, the Netherlnads, September 19/23, 1999. Abstract C52.
Herranz, Y. Chen, L. Cintas, P.E. Hernández, T.J. Montville and M.L. Chikindas. 1999. Mode of action of enterocin P against Enterococcus faecium T136. Sixth Symposium on Lactic Acid Bacteria. Book of Abstracts. Veldhoven, the Netherlnads, September 19/23, 1999. Abstract C40.
T.J. Montville, A. Mazzotta, A. Crandall, K. Modi and M.L. Chikindas. 1999. Mechanism of nisin resistance does not confer intrinsic resistance to heat, preservatives and antibiotics in L. monocytogenes and C. botulinum.  Food Microbiology and Food Safety into the Next Millennium. Proceedings of the Seventeenth ICFMH, Veldhoven, the Netherlands, September 13/17, 1999, p. 281-284.
L. Nilsson, Y. Chen, M.L. Chikindas, H.H. Huss, L. Gram and T.J. Montville. 1999. The combined action of nisin and CO2 atmosphere on the cytoplasmic membrane of Listeria monocytogenes Scott A. Food Microbiology and Food Safety into the Next Millennium. Proceedings of the Seventeenth International Conference of the International Committee on Food Microbiology and Hygiene (ICFMH), Veldhoven, the Netherlands, September 13/17, 1999, p. 195-198.
H.J. Chung, Y.Chen, M.L. Chikindas and T.J. Montville. 1999. Nisin is bactericidal for Mycobacterium smegmatis. Book of Abstracts, 1999 IFT Annual Meeting, Chicago, IL, July 24-28. Abstract 37D-25, p. 99.
G. Green, I. Csalami, L.M.T. Dicks, G. Bruggeman, N. Vekemans, E.J. Vandamme and M.L. Chikindas. 1996. Pediocin PD-1, a bacteriocin produced by Pediococcus damnosus. 5th Symposium on Lactic Acid Bacteria. September 8 -12. Veldhoven, The Netherlands.
C.A. Van Reen, T.L.J. Verellen, G. Bruggeman, L.M.T. Dicks, E.J. Vandamme and M.L. Chikindas. 1996. Preliminary characterization and optimization of production of plantaricin 423, a pediocin-like bacteriocin produced by Lactobacillus plantarum. 5th Symposium on Lactic Acid Bacteria. September 8 -12. Veldhoven, The Netherlands.
R. Kritzinger, L.M.T. Dicks and M.L. Chikindas. 1996. Characterization of the bacteriocin PD-1, produced by Pediococcus damnosus. 8th International Congress of the  Bacteriology and Applied Microbiology Division of the International Union of Microbiological Societies.  August 18 - 23. Jerusalem, Israel.
C.A. Van Reenen, L.M.T. Dicks and M.L. Chikindas. 1996. Genetic characterization of a pediocin-like bacteriocin produced by Lactobacillus plantarum. 8th International Congress of the  Bacteriology and Applied Microbiology Division of the International Union of Microbiological Societies.  August 18 - 23. Jerusalem, Israel.
E. Emond, K. Venema, M. Chikindas, J. Kok, S. Pandian and G. Venema. 1995. Compatibility between pediocin PA-1 and lactococcin A export machineries: study with leader exchange. Bacteriocins of lactic acid bacteria. Applications and fundamentals. April 17-23, 1995. Banff, Alberta, Canada, P13.
M.L. Chikindas, M.J. Garcia, A.J.M. Driessen, J.D. Marugg, A.M. Ledeboer, T. Abee, W.N. Konings, G. Venema and J. Kok. 1993. Pediocin PA-1 from Pediococcus acidilactici PAC1.0: mode of action and genetics. FEMS Microbiology Reviews. Vol. 12/1-3, P123.
M.L. Chikindas, S.V. Isayeva, L.G. Chistyakova, G.F. Rosenblat, E.Yu. Klinsky, V.V. Grabovetsky, V.Yu. Alakhov and V.I. Kiselev. 1990. Cloning and expression of the enterotoxin A gene of Staphylococcus aureus in gram-positive and gram-negative microorganisms. Abstracts of the VII All-Union Symposium "Molecular Mechanisms of Genetical Processes". Moscow. P. 12 (Russian).
M.L. Chikindas, S.V. Isayeva, L.G. Chistyakova, E.Yu. Klinsky, V.V. Grabovetsky, V.Yu. Alakhov and V.I. Kiselev. 1989. Cloning and expression of enterotoxin A gene of Staphylococcus aureus in Escherichia coli and Bacillus subtilis. Abstracts of the II All-Union Conference on Bacterial Toxins. Jurmala. P. 10 (Russian).
V.I. Kiselev, L.G. Chistyakova, M.L. Chikindas, S.V. Isaeva and V.V. Grabovetsky. 1989. Genes regulating proteolysis in cells of Escherichia coli and bacteria of the genus Pseudomonas. Abstracts of the USSR - GDR X Biochemical Symposium. Tashkent. P. 37 (Russian).
I.V. Astafyeva and M.L. Chikindas. 1989. Direct transport of the genetic material into the cell by means of the polyelectrolytic complex. Abstracts of the USSR - GDR X Biochemical Symposium. Tashkent. P. 8 (Russian).
M.L. Chikindas, G.F. Rosenblat, V.A. Eremin and V.I. Kiselev. 1989. Effect of synthesis and secretion in periplasm of heterologous proteins by cells of Escherichia coli on the phospholipid composition of membranes. Abstracts of the All-Union Conference "Regulation of Microbial Metabolism". Puschino. P. 73 (Russian).
I.V. Astafyeva, A.V. Kabanov, M.L. Chikindas, V.I. Kiselev, A.I. Glukhov, S.A. Gordeev, V.A. Izumrudov, E.S. Severin and V.A.Kabanov. 1989. Increasing the efficiency of intracellular translocation of nucleic acids by means of their incorporation in the polyelectrolytic complex. Abstracts of the II All-Union Conference "Interpolymeric complexes". Riga. P. 251 (Russian).
M.L. Chikindas and V.N. Mironov. 1986. Localization of spo- genes in the 210° region of Bacillus subtilis chromosome. Abstracts of the All-Union Conference "Genetics and Biochemistry of Microorganisms -Biotechnologies". Moscow. P. 13 (Russian).
V.N. Mironov, M.L. Chikindas and E.V. Lukyanov. 1986. Localization of the operator and the main promotor of the riboflavin biosynthesis operon in Bacillus subtilis. Abstracts of the All-Union Conference "Genetics and Biochemistry of Microorganisms - Biotechnologies". Moscow. Pp. 11 - 12 (Russian).
M.L. Chikindas and V.N. Mironov. 1986. Identification of the gene, limiting the riboflavin synthesis in Escherichia coli. Abstracts of the All-Union Conference "New Trends in Biotechnology". Puschino. P. 58 (Russian).
A.I. Stepanov, P.M. Rabinovich, M.Ya. Haikinson, L.S. Arutynova, M.L. Chikindas, E.V. Lukyanov, G.I. Morozov and V.V. Emelyanov. 1985. Genetic Engineering of Bacilli. Abstracts of the V All-Union Biochemical Meeting. Moscow. Vol. 1, p. 151 (Russian).
M.L. Chikindas, P.M. Rabinovich and A.I. Stepanov. 1985. Study of the 210° region of the Bacillus subtilis chromosome using recombinant plasmids. Plasmid - X. "Problems of Transport of Genetic Information", Puschino - Moscow. P. 177 (Russian).
M.L. Chikindas, P.M. Rabinovich and Sh.M. Kocharian. 1980. Restriction analysis of DNA's of phage pf16 isolated from Pseudomonas putida presumably lysogenic by pf16. Abstracts of the II Conference of Young Scientists of the Institute of Experimental Biology, Armenian Academy of Sciences. Yerevan. Pp. 105 - 107 (Russian).