Karl R. Matthews, Ph. D.

Faculty Links



1. Yangjin, J., H. Jang, M. Guo, J. Gao, and K. R. Matthews. 2017. Sanitizer efficacy in preventing cross-contamination of heads of lettuce during retail crisping. Food Microbiology.64:179-185.
2. Yangjin, J., J. Gao, H. Jang, M. Guo and K. R. Matthews. 2017. Efficacy of electrolyzed water in preventing cross-contamination during retail preparation of whole and fresh-cut cantaloupe. Food Control. 75:228-235.  http://dx.doi.org/10.1016/j.foodcont.2016.12.009.
3. Jung, Y., and K.R. Matthews. 2016. Transfer of extended spectrum β-lactamase encoding gene, blashv18 gene, between Klebsiella pneumoniae in temperature abused raw foods. Food Microbiology. 60: 39-48.
4. Zhou, Y., M.V. Karwe, and K.R. Matthews. 2016. Differences in inactivation of Escherichia coli strains in ground beef following repeated high pressure processing treatment and cold storage. Food Microbiology. 58: 7-12.
5. Hintz, T., K.R. Matthews, and R. Di. 2015. The use of plant antimicrobial compounds for food preservation. BioMed Research International.  Article ID# 246264. Doi:10.1155/2015/246264.
6.Jung, Y., H. Jang, and K.R. Matthews. 2014. Effect of the food production chain from farm practices to vegetable processing on outbreak incidence. Microbial Biotechnology. 7:517-527.
7. Suo, Y., Y. Liu, X. Zhou, Y. Huang, C. Shi, K. Matthews, and X. Shi. 2014. Impact of sod on the expression of stress-related genes in Listeria monocytogenes 4b G with/without paraquat treatment. J. Food Science. 79:M1745-1749.
8. Seo, S., and K.R. Matthews. 2014. Exposure of Escherichia coli O157:H7 to soil or manure influences capsular polysaccharide production, plant defense response and persistence of that pathogen on plants. Food Microbiology. 38: 87-92
9. Wu, W-H., R. Di, K.R. Matthews. 2013. Activity of the plant-derived peptide Ib-AMP1 and the control of enteric foodborne pathogens. Food Control. 33:142-147.
10. Matthews, K.R. 2013. Sources of enteric pathogen contamination of fruits and vegetables: future directions of research. Stewarts Post Har. Rev. ISSN: 1945-9656; doi: 10.2212/spr2013.1.2.
11. Wu, W-H., R. Di, K.R. Matthews. 2013. Antibacterial  mode of action of Ib-AMP1against Escherichia coli O157:H7. Probiotics Antimicrob. Proteins. DOI 10.1007/s12602-013-9127-1.
12. Tan, Y.N., M.K. Ayob, and K.R. Matthews. 2013. Comparative antibacterial activity of tryptic-hydrolyzed palm kernel cake proteins with different degrees of hydrolysis. J. Food Quality.  36:447-456. DOI: 10.1111/jfq.12061
13. Wu, W-H., and K.R. Matthews. 2013. Susceptibility of aged guinea pigs to repeated daily challenge with Listeria monocytogenes. Foodborne Dis. Infect.  10:284-289.  [Matthews developed the project, secured funding for the project, and directed Wu (graduate students) in the laboratory. Wu conducted the research, analyzed the data, and co-wrote the draft of the manuscript with Matthews.]
14. Tan, Y.N., K.R. Matthews, R. Di, and M.K. Ayob. 2012. Comparative antibacterial mode of action of purified alcalase-and tryptic-hydrolyzed palm kernel cake proteins on the foodborne pathogen Bacillus cereus.  Food Control. 31:53-58. http://dx.doi.org/10.1016/j.foodcont.2012.09.042
15. Wu, W-H., H-J Pang, and K. R. Matthews. 2012. Immune status and development of Listeria monocytogenes infection in aged and young guinea pigs. Clin. Invest. Med. 35:E309-E321.
16. Seo, S., and K.R. Matthews. 2012. Plant defense response to Escherichia coli O157:H7 cell surface structures influences survival of the enteric pathogen on plant surfaces. Appl. Envir. Microbiol. 78:5882-5889.
17. Tan, Y.N., M.K. Ayob, M.A. Osma, and K.R. Matthews. 2012. Bacteriostatic mode of action of trypsin-hydrolyzed palm kernel expeller peptide against Bacillus cereus. Probiotics and Anitmicrobial proteins. 4:59-65.
18. Tan, Y.N., M.K. Ayob, M.A. Osma, and K.R. Matthews. 2011. Antibacterial activity of different degree of hydrolysis of palm kernel expeller peptides against spore-forming and non-spore- forming bacteria. Lett. Appl. Micro. 53:509-517.
19. Christensen, E., and K.R. Matthews. 2011. Secondary transfer and expression of vanA in Enterococcus faecium derived from a commensal vancomycin-susceptible E. faecium multi-component food isolate. Microbial Drug Resis. 17: 369-376.
20. Riazi, S., and K.R. Matthews. 2010. Failure of foodborne pathogens to develop resistance to sanitizers following repeated exposure to common sanitizers.  Inter. Biodeter. & Biodegrad. 65:374-378 (Doi:10.1016/jibiod.2010.12.001).
21. Buchholz, A., and K.R. Matthews. 2010. Reduction of Salmonella on alfalfa seeds using peroxyacetic acid and a commercial seed washer is as effective as treatment with 20,000 ppm Ca(OCl)2. Lett. Appl. Micro. S1: 426-468.
22. Murdock, C., M. Chikindas, and K.R. Matthews. 2010. The Pepsin Hydrolysate of bovine Lactoferrin (LfH) interacts with the Cytoplasmic Membrane and causes a Collapse of the Membrane Potential in E. coli O157:H7. J. Probiotics and Antimicrobial Proteins. 2:112-119.
23. Mootian G., W-H. Wu, and K.R. Matthews. 2009. Transfer of Escherichia coli O157:H7 from Soil, Water, and Manure Contaminated with Low Numbers of the Pathogen to Lettuce Plants of Varying Age J. Food Prot. 72:2308-2312.
24. Christensen, E.A., K. Joho, and K.R. Matthews. 2008. Streptogramin resistance and virulence determinants in vancomycin-susceptible enterococci isolated from blended deli salads. J. Appl. Micro. 104:1260-1265.
25. Hartog, E., L. Ben-Shalom, D. Shachar, K.R. Matthews, and S. Yaron. 2008. Regulation of marA, soxS, rob, arcAB and micF in Salmonella enteric serovar Typhimurium. Microbiol Immun. 52:565-574.
26. Kolling, G.L., and K.R. Matthews. 2007. Influence of enteric bacteria conditioned media on recovery of Escherichia coli O157:H7 exposed to starvation and sodium hypochlorite. J. Applied Microbiol. 103:1435-1441.
27. Pang, H-J., C. J. Potenski, and K.R. Matthews. 2007. Exposure of Listeria monocytogenes to food and temperature abuse using a dialysis tubing culture method. J. Food Safety. 27:426-444.
28. Murdock, C.A., J. Cleveland, K.R. Matthews, and M.L. Chikindas. 2007. The synergistic effect of nisin and lactoferrin on the inhibition of Listeria monocytogenes and Escherichia coli O157:H7. Lett. Appl. Microbiol. 44:255-261.
29. Pang, H-J., C-Y. Lo, and K.R. Matthews. 2007. Influence of immunomodulation on the development of Listeria monocytogenes infection in aged guinea pigs. FEMS Immun. Med Microbiol. 49:415-422.
30. Tabak, M., K., Scher, E. Hartog, U. Romling, K.R. Matthews, M. Tchikindas, S. Yaron. 2007. The effect of triclosan on Salmonella Typhimurium at different growth stages and in biofilms. FEMS Micro. Lett. 267:200-206.
31. Pang, H-J., and K.R. Matthews. 2006. Influence of a food environment on Listeria monocytogenes infection in the Guinea pig model J. Food Safety. 26:313-324.
32. Solomon, E.B., and K.R. Matthews. 2006. Interaction of live and dead Escherichia coli O157:H7 and fluorescent microspheres with lettuce tissue suggests bacterial processes do not mediate adherence. Lett. Appl. Microbiol. 42:88-93.
33. Solomon, E.B., and K.R. Matthews. 2005. Use of fluorescent microspheres as a tool to investigate bacterial interactions with growing plants. J. Food Protect. 68:870-873.
34. Golding, S.S., and K.R. Matthews. 2004. Intrinsic mechanism decreases sensitivity of Escherichia coli O157:H7 to multiple antibiotics. J. Food Prot. 67:34-39.
35. Solomon, H-J. Pang, and K.R. Matthews. 2003. Persistence of Escherichia coli O157:H7 on lettuce plants following spray irrigation with contaminated water J. Food Protect. 66:2198-2202.
36. Gandhi, M., and K.R. Matthews. 2003. Efficacy of chlorine and calcinated calcium treatment of alfalfa seeds and sprouts to eliminate Salmonella. Inter. J. Food Microbiol. 87:301-306.
37. Potenski, C.J, M. Gandhi, and K.R. Matthews. 2003. Exposure of Salmonella Enteritidis to chlorine or food preservatives decreases susceptibility to antibiotics. FEMS Microbiol. Lett. 220:181-186.
38. Yaron, S., D.G. White, and K.R. Matthews. 2003. Characterization of an Escherichia coli O157:H7 marR mutant. Inter. J. Food Microbiol. 85:281-291.
39. Li, J., G.L. Kolling, K.R. Matthews, and M.L. Tchikindas. 2003. Cold and 100% carbon dioxide used as multi-hurdle preservation do not induce appearance of viable but non-culturable Listeria monocytogenes. J. Appl. Microbiol. 94:48-53.
40. Murdock, C., and K.R. Matthews. 2002. Antibacterial Activity of Pepsin-Digested Lactoferrin on Foodborne Pathogens in Buffered Broth Systems and UHT Milk with EDTA. J. Appl. Microbiol. 93:850-856.
41. Solomon, E. B., E.B., C.J. Potenski, and K.R. Matthews. 2002. Effect of irrigation method on transmission to and persistence of Escherichia coli O157:H7 on lettuce. J. Food Prot. 65:673-676.
42. Yaron, S., and K.R. Matthews. 2002. A reverse transcriptase-PCR assay for detection of viable Escherichia coli O157:H7. J. Appl. Microbiol. 92:663-640.
43. Solomon, E.B., S. Yaron, and K.R. Matthews. 2002. Transmission and internalization of Escherichia coli O157:H7 from contaminated manure and irrigation water into lettuce plant tissue. Appl. Environ. Microbiol. 68:397-400.
44. Kolling, G., and K.R. Matthews. 2001. Examination of recovery in vitro and in vivo of nonculturable Escherichia coli O157:H7. Appl. Environ. Microbiol. 67:3928-3933.
45. Gandhi, M., S. Golding, S. Yaron, and K.R. Matthews. 2001. Use of green fluorescent protein expressing Salmonella Stanley to investigate survival, spatial location, and control on alfalfa sprouts. J. Food Prot. 64:1891-1898.
46. Zhao, L., and K.R. Matthews. 2000. Influence of starvation, temperature, and pH on culturability of Escherichia coli O157:H7. J. Food safety. 20:191-205.
47. Yaron, S., G.L. Kolling, L. Simon, and K.R. Matthews. 2000. Vesicle transfer of virulence genes from Escherichia coli O157:H7 to other enteric bacteria. Appl. Environ. Microbiol.66:4414-4420.


  1. Montville, T.J., and K.R. Matthews (editors) 2014. 기초식품미생물학. Published by 월드사이언스   Korean version of Food Microbiology: An introduction. see below.
  2. Montville, T. J. and K.R. Matthews (editors) 2011. 食物微生物学:Jointly published by ScienceP (China) and the American Society for Microbiology Press (US.). Chinese version of Food Microbiology: An introduction. See below.
  3. Montville, T.J. and K.R. Matthews (Editors). 2009. Microbiologia de los alimentos. Introduccion. Editorial Acirbia, Zaragoza, Spain. Spanish version of “Food Microbiology: An introduction.” See below.
  4. Montville, T.J. and K.R. Matthews (Editors). 2005. Food Microbiology: An Introduction. 1st Edition. (2005). American Society for Microbiology Press. *2nd edition published in 2008. #3rd edition published in 2012, Montville, T.J., K.R. Matthews, K. Kniel. (Editors).


  1. Matthews, K.R., G. Sapers, and C. Gerba (Editors). 2014. 2nd Edition. The Produce Contamination Problem: Causes and Solutions. Academic Press.
  2. Sapers, G., E. Solomon, and K.R. Matthews (Editors). 2009. The Produce Contamination Problem: Causes and Solutions. Academic Press.
  3. Matthews, K.R. (Editor). 2008. Microbiologia de las frutas y las verduras frescas. Editorial ACRIBIA, S.A. Spanish version of “Microbiology of Fresh Produce”. See #3 below.
  4. Matthews, K.R. (Editor). 2006. Emerging Issues in Food Safety. Microbiology of Fresh Produce. American Society for Microbiology Press.


  1. Jung, Y., and K.R. Matthews. 2014. Application of natural antimicrobial compounds to enhance the microbial safety of fresh and minimally processed produce. In: Innovations in postharvest technology. Ed. S. Pareek. CRC Press. USA.
  2. Jung, Y., and K.R. Matthews. 2014. Development and application of novel antimicrobials in food and food processing. In: Antimicrobial resistance and food safety methods and techniques. Eds. C. Chen, X. Yan, and C.R. Jackson. Elsevier Inc.
  3. Matthews, K.R. 2014. Food Safety - A global perspective. In: Practical Food Safety: Contemporary Issues and Future Directions. Eds. R. Bhat and V. Gomez-Lopez. Pages. Wiley-Blackwell.
  4. Matthews, K.R. 2009. Leafy Vegetables. In: The Produce Contamination Problem: Causes and Solutions. Eds. Sapers, Solomon, and Matthews. Pages 165-188. Academic Press.
  5. Montville, T.J., and K.R. Matthews. 2007.  Growth, survival, and death of microbes in foods. In:  Food Microbiology Fundamentals and Frontiers. 3nd Edition. Eds. Doyle and Beuchat. pages 3 – 22. ASM Press.
  6. Matthews, K.R. 2006. Microorganisms associated with fresh fruits and vegetables. In: Microbiology of Fresh Produce. Ed. Matthews. Pages 1-20. ASM Press.
  7. Matthews, K.R., 2005. Detection and Enumeration of Microbes in Food. In: Food Microbiology: An Introduction. Eds. Montville and Matthews. 1st ed. pages 45- 51. 2nd ed. pages 57-64. ASM Press.
    [Matthews determined the content of the chapter and independently wrote the chapter.]
  8. Matthews, K.R., 2005. Rapid and Automated Microbial Methods. In: Food Microbiology: An Introduction. Eds. Montville and Matthews. 1st ed. pages 53- 64. 2nd ed. pages 65-76. ASM Press.
  9. Matthews, K.R., 2005. Industrial strategies of ensuring safe food. In: Food Microbiology: An Introduction. Eds. Montville and Matthews. 1st ed. pages 345-358. 2nd ed. pages 387-402. ASM Press.
  10. Matthews, K.R. 2002. Rapid methods for microbial detection in minimally processed food. In: Microbial Safety of Minimally Processed Foods. Eds. Novak, Sapers, and Junja. pages 151 – 164. CRC Press.
  11. Montville, T.J., and K.R. Matthews. 2001. Principles which influence microbial growth, survival, and death in foods. In: Food Microbiology Fundamentals and Frontiers. Eds. Doyle, Beuchat, and Montville. 2nd Edition. pages 13 – 32. ASM Press.