![[Dept. of Food Science]](http://njaes.rutgers.edu/_common/images/subheads/foodscience.gif "[Dept. of Food Science]"){kind=small}
Publications
2. Rafi MM, Yadav PN, Reyes M. Lycopene inhibits LPS induced pro-inflammatory mediators in mouse macrophage cells. Journal of Food Science, 72: 69-74 (2007).
3. Rafi MM,Vastano BC. Identification of a structure specific Bcl-2 phosphorylating homoisoflavone molecule from Vietnamese coriander (Polygonatum odoratum) that induces apoptosis anG2/M cell cycle arrest in breast cancer cell lines, Food Chemistry, 104: 332-340 (2007).
4. Rafi MM, Shafaie Y. Dietary Lutein modulates inducible nitric oxide synthase (iNOS) gene and protein expression in mouse macrophage cells (RAW 264.7). Molecular Nutrition and Food Research, 51(3): 333-340 (2007).
5.
Bonnet M, Rafi MM, Chikindas ML, Montville TJ. Bioenergetic mechanism of nisin resistance, induced by the acid tolerance response of Listeria monocytogenes. Applied and Environmental Microbiology, 72 (4): 2556-2563 (2006).
6. Yu H, Rafi MM, Ho CT. Targeting inflammation using Asian herbs. Herbs: Challenges in Chemistry and Biology. Edited by Mingfu Wang, Shengmin Sang, Lucy Sun Hwang and Chi-Tang Ho. ACS Symposium Series 925, American Chemical Society: Washington, D.C., pp266-280 (2006).
7.
Matchanickal RA, Rafi MM. Curcumin: Potential health benefits, molecular mechanism of action, and its anticancer properties in vitro and in vivo. Herbs: Challenges in Chemistry and Biology. Edited by Mingfu Wang, Shengmin Sang, Lucy Sun Hwang and Chi-Tang Ho. ACS Symposium Series 925, American Chemical Society: Washington, DC, 92-107 (2006).
8. Rafi MM, Bai NS, Ho CT, Rosen RT, White E, Perez D, DiPaola RS. A Sesquiterpenelactone from Inula Britannica induces anti-tumor effects dependent on Bcl-2 phosphorylation. Anticancer Research, 25: 313-318 (2005).
9.
Morris MJ, Cardo CC, Kelly WK, Slovin SF, Siedlecki K, Regan KP, DiPaola RS, Rafi MM, Rosen N, Scher HI. Safety and biologic activity of intravenous BCL-2 antisense oligonucleotide (G3139) and taxane chemotherapy in patients with advanced cancer. Appl Immunohistochem Mol Morphol, 13(1): 6-13 (2005).
10. Rafi MM. Elucidating the role of Nutraceuticals in overexpressing anti-apoptotic proteins in prostate cancer. Nutrition, Nutrigenomics Special issue, 20: 78-82 (2004).
11. Rafi MM. Significance of Bcl-2 protein phosphorylation in cancer cells for pharmaceutical and nutraceutical discovery. Food Factors in Health Promotion and Disease Prevention. Edited by Fereidoon Shahidi, Chi-Tang Ho, Shaw Watanabe and Toshihiko Osawa. ACS Symposium Series 851, American Chemical Society: Washington, D.C., pp 72-85 (2003).
12. Yadav PN, Liu Z, Rafi MM. A diarylheptanoid from Lesser Galangal (Alpinia officinarum) inhibits proinflammatory mediators via inhibition of mitogen-activated protein kinase, p44/42, and transcription factor nuclear factor-kappa B. J Pharmacol Exp Ther, 305(3): 925-931 (2003).
13. Rafi MM, Yadav PN, Maeng IL. Targeting Inflammation using Nutraceuticals. Oriental Foods and Herbs-Chemistry and Health effects. Edited by Chi-Tang Ho, Jen-Kun Lin and Qun Yi Zheng, ACS Symposium Series No 859, American Chemical Society: Washington, D.C., pp 48-63 (2003).
14. Ho CT, Rafi MM, DiPaola RS, Ghai G, Rosen RT, Bai N. Inducing cell apoptosis and treating cancer using 1-0-acetylbritannilactone or 1,6-0,0-diacetylbritannilactone. United States Patent Publication: 6,627,623 dt Sept 30, (2003).
15. Liu Z, Rafi MM, Zhu N, Ryu K, Sang S, Ho CT, Rosen RT. Separation and bioactivity of diarylheptanoids from Lesser Galangal (Alpinia officinarum). Food Factors in Health Promotion and Disease Prevention. Edited by Fereidoon Shahidi, Chi-Tang Ho, Shaw Watanabe and Toshihiko Osawa. ACS Symposium Series 851, American Chemical Society: Washington, D.C., pp.369-380 (2003).
16. Rosen RT, Ho CT, DiPaola RS, Rafi MM, Ghai G, Vastano BC. Use of 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4'-hydroxyphenyl) as an anticarcinogenic agent. United States Patent publication: 6,498,195, dt Dec 24, (2002).
17. Vastano BC, Rafi MM, DiPaola RS, Zhu N, Ho CT, Rella AT, Ghai G, Rosen RT. Bioactive homoisoflavonoids from Vietnamese coriander or Pak Pai (Polygonum odoratum). Quality Management of Nutraceuticals. Edited by Chi-Tang Ho and Qun Yi Zheng. ACS Symposium Series 803, American Chemical Society: Washington, D.C., pp. 269-280 (2002).
18. Zhu N, Rafi MM, Li D, LaVoie EJ, DiPaola RS, Badmaev V, Ghai G, Rosen RT, Ho CT. Analysis of bioactive ferulates from Gum Guggul (Commiphora wightii). In Quality Management of Nutraceuticals. Edited by Chi-Tang Ho and Qun Yi Zheng. ACS Symposium Series 803, American Chemical Society: Washington, D.C., pp. 281-291 (2002).
19. Rafi MM, Vastano BC, Zhu N, Ho CT, Ghai G, Rosen RT, Gallo MA, DiPaola RS. Novel polyphenol molecule isolated from Licorice root (Glycrrhiza glabra) induced apoptosis, G2/M cell cycle arrest and bcl-2 phosphorylation in tumor cell lines. Journal of Agricultural and Food Chemistry 50 (4): 677-684 (2002). (Selected as one of the top 25 papers by the Office of Dietary Supplements division of National Institute of Health in 2002).
20. Morris MJ, Tong WP, Cardo CC, Drobnjak M, Kelly WK, Slovin S, Terry KL, Swanson P, Rafi MM, DiPaola RS, Rosen N, Scher HI. A phase I trial of Bcl-2 antisense oligonucleotide (G3139) administrated by continuous infusion in patients and advanced cancer. Clin Cancer Res, 8: 679-683 (2002).
21. Rafi MM. Nutragenomics: Development of Personalized Foods for the Future? Institute of Food Technologists, Newsletter, volume 2, issue 1, pp 6-7 (2002).
22. Zhu N, Rafi MM, DiPaola RS, Xin J, Chin CK, Badmaev V, Ghai G, Rosen RT, Ho CT. Bioactive constituents from Gum Guggul (Commiphora wightii). Phytochemistry. 56 (7): 723-727 (2001).
23. DiPaola RS, Patel J, Rafi MM. Targeting apoptosis in prostate cancer. Hematology Oncology Clinics of North America, 15(3): 509-524 (2001).
24. Zhu N, Kikuzaki H, Sheng S, Sang S, Rafi MM, Wang M, Nakatani N, DiPaola RS, Rosen RT, Ho CT. Furanosesesquiterpenoids of Commiphora myrrha. Journal of Natural Products. 64: 1460-1462 (2001).
25. Rafi MM, Rosen RT, Vassil A, Ho CT, Zhang H, Ghai G, Lambert G, DiPaola RS. Modulation of bcl-2 and cytotoxicity by Licochalcone-A, a novel estrogenic flavonoid. Anticancer Research, 20: 2653-2658 (2000).
26. DiPaola RS, Rafi MM, Vyas V, Gupta E, Toppmeyer D, Rubin E, Patel G, Goodin S, Medina M, Medina P, Zamek R, Zhang C, White E, Hait WN. Phase I clinical and pharmacologic study of 13-cis retinoic acid, alpha interferon and paclitaxel in patients with prostate cancer and other advanced malignancies. J Clin Oncol, 17: 2213-2218 (1999).
27. Thomas E, Shunmugam J, Rafi MM. In vitro antibacterial activity of certain medicinal plants of Kerala. Biomedicine, 9(3):185-190 (1999).
28. DiPaola RS, Zhang H, Lambert G, Meeker R, Licitra E, Rafi MM, Zhu BT, Spaulding H, Goodin S, Toledano MB, Hait WN, Gallo MA. Clinical and biological activity of an estrogenic herbal combination (PC-SPES) in prostate cancer. N Engl J Med, 339:785-791 (1998).
29. Thomas E, Shunmugam J, Rafi MM. Antibacterial activity of plants belonging to Zingiberaceae family. Biomedicine, 16 (2&3): 15-20 (1996).
30. Rafi MM, Raj, RK. Phosphoenolpyruvate-succinate-glyoxylate pathway in filarial parasite Setaria digitata. Journal of Biosciences 16(3): 121-126 (1991).