Present - 2020
Stukey, G. J., M. R. Breuer, N. Burchat, R. Jog, K. Schultz, G.-S. Han, M. S. Sachs, H. Sampath, R. Marmorstein, and G. M. Carman 2024. The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases. J. Lipid Res. 65: 100711. Reprint
Jog, R., G.-S. Han, and G. M. Carman. 2024. The CTR hydrophobic residues of Nem1 catalytic subunit are required to form a protein phosphatase complex with Spo7 to activate yeast Pah1 PA phosphatase. J. Biol. Chem. 300: 108003. Reprint
Stukey, G. J., G.-S. Han, and G. M. Carman. 2024. Architecture and function of yeast phosphatidate phosphatase Pah1 domains/regions. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1869: 159547. Reprint
Khondker, S., G.-S. Han, and G. M. Carman. 2024. Protein kinase Hsl1 phosphorylates Pah1 to inhibit phosphatidate phosphatase activity and regulate lipid synthesis in Saccharomyces cerevisiae. J. Biol. Chem. 300: 107572. Reprint
Jog, R., G.-S. Han, and G. M. Carman. 2024. The Saccharomyces cerevisiae Spo7 basic tail is required for Nem1-Spo7/Pah1 phosphatase cascade function in lipid synthesis. J. Biol. Chem. 300: 105587. Reprint
Han, G.-S., J. M. Kwiatek, K. S. Hu, and G. M. Carman. 2024. Catalytic core function of yeast Pah1 phosphatidate phosphatase reveals structural insight into its membrane localization and activity control. J. Biol. Chem. 300: 105560. Reprint
Stukey, G. J., G.-S. Han, and G. M. Carman. 2023. Phosphatidate phosphatase Pah1 contains a novel RP domain that regulates its phosphorylation and function in yeast lipid synthesis. J. Biol. Chem. 299: 105025. Reprint
Dhakephalkar, T., G. J. Stukey, Z. Guan, G. M. Carman, and E. A. Klein. 2023. Characterization of an evolutionarily distinct bacterial ceramide kinase from Caulobacter crescentus. J. Biol. Chem. 299: 104894. Reprint
Jog, R., G.-S. Han, and G. M. Carman. 2023. Conserved regions of the regulatory subunit Spo7 are required for Nem1-Spo7/Pah1 phosphatase cascade function in yeast lipid synthesis. J. Biol. Chem. 299: 104683. Reprint
Kwiatek, J. M., B. Gutierrez, E. C. Izgu, G.-S. Han, and G. M. Carman 2022. Phosphatidic acid mediates the Nem1-Spo7/Pah1 phosphatase cascade in yeast lipid synthesis. J. Lipid Res. 63: 100282. Reprint
Pokharel, M., P. Konarzewska, J. Y. Roberge, G.-S. Han, Y. Wang, G. M. Carman, and C. Xue. 2022. The anticancer drug bleomycin shows potent antifungal activity by altering phospholipid biosynthesis. Microbiol. Spectr. 10: e0086222. Reprint
Khondker, S., J. M. Kwiatek, G.-S. Han, and G. M. Carman. 2022. Glycogen synthase kinase homolog Rim11 regulates lipid synthesis through the phosphorylation of Pah1 phosphatidate phosphatase in yeast. J. Biol. Chem. 298: 102221. Reprint
Park, Y., G. J. Stukey, R. Jog, J. M. Kwiatek, G.-S. Han, and G. M. Carman. 2022. Mutant phosphatidate phosphatase Pah1-W637A exhibits altered phosphorylation, membrane association, and enzyme function in yeast. J. Biol. Chem. 298: 101578. Reprint
Khondker, S., G-S. Han, and G. M. Carman. 2022. Phosphorylation-mediated regulation of the Nem1-Spo7/Pah1 phosphatase cascade in yeast lipid synthesis. Adv. Biol. Regul. 84: 100889. Reprint
Carman, G. M. 2021. Lipid metabolism has been good to me. J. Biol. Chem. 297: 100786. Reprint
Dey, P., G.-S. Han, and G. M. Carman. 2020. A review of phosphatidate phosphatase assays. J. Lipid Res. 61: 1556-1564. Reprint
Kwiatek, J. M., G.-S. Han, and G. M. Carman. 2020. Phosphatidate-mediated regulation of lipid synthesis at the nuclear/endoplasmic reticulum membrane. Biochim. Biophys. Acta Mol. Cell Biol. Lipids. 1865: 158434. Reprint
Mirheydari, M., P. Dey, G. J. Stukey, Y. Park, G.-S. Han, G. M. Carman. 2020. The Spo7 sequence LLI is required for Nem1-Spo7/Pah1 phosphatase cascade function in yeast lipid metabolism. J. Biol. Chem. 295: 11473-11485. Reprint
Kwiatek, J. M., G. M. Carman. 2020. Yeast phosphatidic acid phosphatase Pah1 hops and scoots along the membrane phospholipid bilayer. J. Lipid Res. 61: 1232-1243. Reprint